Tadalafil: Price, Pros & Cons in the UK
Known as the 'weekend pill' for lasting up to 36 hours — the generic version of Cialis.
Quick Facts
- ED — the weekend pill
- Typical cost: £15–£35/mo
- 17 providers currently offer this
- Content last reviewed 13 August 2026
This page provides general information, not medical advice — whether any treatment is right for you is a decision for a UK-registered prescriber after reviewing your individual history.
What it is
Tadalafil is the generic version of Cialis, available as an as-needed tablet or a lower daily dose. Its effects last far longer than sildenafil, up to 36 hours, giving more flexibility around when sex happens.
Pros and cons
Why it's good
- Lasts up to 36 hours, versus around 4 hours for sildenafil
- Not significantly affected by food, unlike sildenafil
- A daily low-dose version is available, removing the need to plan around taking a tablet before sex
- Can start working in as little as 30 minutes
Why it's not for everyone
- Generally costs more than generic sildenafil
- Same nitrate interaction warning as other PDE5 inhibitors applies
- Common side effects include headaches, indigestion, back pain and muscle aches
- The longer duration means side effects, if they occur, also last longer
Who it's best for
Men who want more spontaneity rather than planning sex around a single dose, or who find sildenafil's food restrictions inconvenient.
Typical cost
Providers offering this
- Numan
- Voy (formerly Manual)
- ZAVA
- Asda Online Doctor
- Boots Online Doctor
- LloydsPharmacy Online Doctor
- Superdrug Online Doctor
- Dr Fox
- Pharmacy2U
- Simple Online Pharmacy
- Ashcroft Pharmacy
- Chemist4U
- Medino
- Oxford Online Pharmacy
- The Online Clinic
- Happy Pharmacy
- The Care Pharmacy
Frequently asked questions
What is Tadalafil?
Tadalafil is the generic version of Cialis, available as an as-needed tablet or a lower daily dose. Its effects last far longer than sildenafil, up to 36 hours, giving more flexibility around when sex happens.
How much does Tadalafil cost in the UK?
Tadalafil typically costs £15–£35/mo in the UK, though the exact price depends on dose and provider.
Who is Tadalafil best suited to?
Men who want more spontaneity rather than planning sex around a single dose, or who find sildenafil's food restrictions inconvenient.
Sources
- NHS website — medicines information.
- Electronic Medicines Compendium (emc) — Summary of Product Characteristics for the licensed product.
- Medicines and Healthcare products Regulatory Agency (MHRA) — UK licensing and safety information.
Ready to compare Tadalafil?
See exactly which UK providers offer it, and at what price.
PickMyClinic is an independent comparison site, not a pharmacy or clinic. This page is not a personal recommendation and does not replace advice from a UK-registered prescriber. Some links on this site may be affiliate links; see our Affiliate Disclosure.